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Effects of PPARγ ligands on TGF-β1-induced epithelial-mesenchymal transition in alveolar epithelial cells

BACKGROUND: Transforming growth factor β1 (TGF-β1)-mediated epithelial mesenchymal transition (EMT) of alveolar epithelial cells (AEC) may contribute to lung fibrosis. Since PPARγ ligands have been shown to inhibit fibroblast activation by TGF-β1, we assessed the ability of the thiazolidinediones ro...

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Detalles Bibliográficos
Autores principales:	Tan, Xiahui, Dagher, Hayat, Hutton, Craig A, Bourke, Jane E
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844370/ https://www.ncbi.nlm.nih.gov/pubmed/20178607 http://dx.doi.org/10.1186/1465-9921-11-21

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