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Regulatory T Cell Suppression of Gag-Specific CD8(+) T Cell Polyfunctional Response After Therapeutic Vaccination of HIV-1-Infected Patients on ART

We tested the hypothesis that therapeutic vaccination against HIV-1 can increase the frequency and suppressive function of regulatory, CD4(+) T cells (Treg), thereby masking enhancement of HIV-1-specific CD8(+) T cell response. HIV-1-infected subjects on antiretroviral therapy (N = 17) enrolled in a...

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Detalles Bibliográficos
Autores principales:	Macatangay, Bernard J. C., Szajnik, Marta E., Whiteside, Theresa L., Riddler, Sharon A., Rinaldo, Charles R.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844424/ https://www.ncbi.nlm.nih.gov/pubmed/20352042 http://dx.doi.org/10.1371/journal.pone.0009852

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