Amelioration of Symptoms and Reduction of VIP Levels after Hepatic Artery Chemoembolization in a Patient with Sandostatin Resistant VIPoma

Vasoactive intestinal polypeptide secreting islet cell tumors (VIPomas) are neuroendocrine tumors that secrete excessive amounts of vasoactive intestinal polypeptide (VIP) that cause distinct syndromes characterized by large-volume diarrhea, hypokalemia, and dehydration. The annual incidence of thes...

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Autores principales: Shaib, Walid, Mitchell, Kisha, Saif, M. Wasif
Formato: Texto
Lenguaje:English
Publicado: YJBM 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844690/
https://www.ncbi.nlm.nih.gov/pubmed/20351979
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author Shaib, Walid
Mitchell, Kisha
Saif, M. Wasif
author_facet Shaib, Walid
Mitchell, Kisha
Saif, M. Wasif
author_sort Shaib, Walid
collection PubMed
description Vasoactive intestinal polypeptide secreting islet cell tumors (VIPomas) are neuroendocrine tumors that secrete excessive amounts of vasoactive intestinal polypeptide (VIP) that cause distinct syndromes characterized by large-volume diarrhea, hypokalemia, and dehydration. The annual incidence of these tumors is estimated to be about one per 10,000,000 individuals in the general population. We report a successful treatment of VIPoma with hepatic chemoembolization of a metastatic hepatic lesion evidenced by a reduction of VIP levels and resolutions of symptoms in a patient with pancreatic VIPoma unresponsive to increased doses of an octreotide analog.
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spelling pubmed-28446902010-03-29 Amelioration of Symptoms and Reduction of VIP Levels after Hepatic Artery Chemoembolization in a Patient with Sandostatin Resistant VIPoma Shaib, Walid Mitchell, Kisha Saif, M. Wasif Yale J Biol Med Case Report Vasoactive intestinal polypeptide secreting islet cell tumors (VIPomas) are neuroendocrine tumors that secrete excessive amounts of vasoactive intestinal polypeptide (VIP) that cause distinct syndromes characterized by large-volume diarrhea, hypokalemia, and dehydration. The annual incidence of these tumors is estimated to be about one per 10,000,000 individuals in the general population. We report a successful treatment of VIPoma with hepatic chemoembolization of a metastatic hepatic lesion evidenced by a reduction of VIP levels and resolutions of symptoms in a patient with pancreatic VIPoma unresponsive to increased doses of an octreotide analog. YJBM 2010-03 2010-03 /pmc/articles/PMC2844690/ /pubmed/20351979 Text en Copyright ©2010, Yale Journal of Biology and Medicine https://creativecommons.org/licenses/by-nc/3.0/This is an open access article distributed under the terms of the Creative Commons CC BY-NC license, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use the material for commercial purposes.
spellingShingle Case Report
Shaib, Walid
Mitchell, Kisha
Saif, M. Wasif
Amelioration of Symptoms and Reduction of VIP Levels after Hepatic Artery Chemoembolization in a Patient with Sandostatin Resistant VIPoma
title Amelioration of Symptoms and Reduction of VIP Levels after Hepatic Artery Chemoembolization in a Patient with Sandostatin Resistant VIPoma
title_full Amelioration of Symptoms and Reduction of VIP Levels after Hepatic Artery Chemoembolization in a Patient with Sandostatin Resistant VIPoma
title_fullStr Amelioration of Symptoms and Reduction of VIP Levels after Hepatic Artery Chemoembolization in a Patient with Sandostatin Resistant VIPoma
title_full_unstemmed Amelioration of Symptoms and Reduction of VIP Levels after Hepatic Artery Chemoembolization in a Patient with Sandostatin Resistant VIPoma
title_short Amelioration of Symptoms and Reduction of VIP Levels after Hepatic Artery Chemoembolization in a Patient with Sandostatin Resistant VIPoma
title_sort amelioration of symptoms and reduction of vip levels after hepatic artery chemoembolization in a patient with sandostatin resistant vipoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844690/
https://www.ncbi.nlm.nih.gov/pubmed/20351979
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AT mitchellkisha ameliorationofsymptomsandreductionofviplevelsafterhepaticarterychemoembolizationinapatientwithsandostatinresistantvipoma
AT saifmwasif ameliorationofsymptomsandreductionofviplevelsafterhepaticarterychemoembolizationinapatientwithsandostatinresistantvipoma

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