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Impact of rs361072 in the Phosphoinositide 3-Kinase p110β Gene on Whole-Body Glucose Metabolism and Subunit Protein Expression in Skeletal Muscle

OBJECTIVE: Phosphoinositide 3-kinase (PI3K) is a major effector in insulin signaling. rs361072, located in the promoter of the gene (PIK3CB) for the p110β subunit, has previously been found to be associated with homeostasis model assessment for insulin resistance (HOMA-IR) in obese subjects. The aim...

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Detalles Bibliográficos
Autores principales:	Ribel-Madsen, Rasmus, Poulsen, Pernille, Holmkvist, Johan, Mortensen, Brynjulf, Grarup, Niels, Friedrichsen, Martin, Jørgensen, Torben, Lauritzen, Torsten, Wojtaszewski, Jørgen F.P., Pedersen, Oluf, Hansen, Torben, Vaag, Allan
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844820/ https://www.ncbi.nlm.nih.gov/pubmed/20107106 http://dx.doi.org/10.2337/db09-1359

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