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The Natural Protective Mechanism Against Hyperglycemia in Vascular Endothelial Cells: Roles of the Lipid Peroxidation Product 4-Hydroxydodecadienal and Peroxisome Proliferator–Activated Receptor δ

OBJECTIVE: Vascular endothelial cells (VECs) downregulate their rate of glucose uptake in response to hyperglycemia by decreasing the expression of their typical glucose transporter GLUT-1. Hitherto, we discovered critical roles for the protein calreticulin and the arachidonic acid–metabolizing enzy...

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Detalles Bibliográficos
Autores principales:	Riahi, Yael, Sin-Malia, Yoav, Cohen, Guy, Alpert, Evgenia, Gruzman, Arie, Eckel, Juergen, Staels, Bart, Guichardant, Michel, Sasson, Shlomo
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844828/ https://www.ncbi.nlm.nih.gov/pubmed/20107107 http://dx.doi.org/10.2337/db09-1207

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