Involvement of MicroRNAs in the Cytotoxic Effects Exerted by Proinflammatory Cytokines on Pancreatic β-Cells

OBJECTIVE: Pancreatic β-cells exposed to proinflammatory cytokines display alterations in gene expression resulting in defective insulin secretion and apoptosis. MicroRNAs are small noncoding RNAs emerging as key regulators of gene expression. Here, we evaluated the contribution of microRNAs to cyto...

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Detalles Bibliográficos
Autores principales: Roggli, Elodie, Britan, Aurore, Gattesco, Sonia, Lin-Marq, Nathalie, Abderrahmani, Amar, Meda, Paolo, Regazzi, Romano
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844845/
https://www.ncbi.nlm.nih.gov/pubmed/20086228
http://dx.doi.org/10.2337/db09-0881

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