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Increased CYP2J3 Expression Reduces Insulin Resistance in Fructose-Treated Rats and db/db Mice
OBJECTIVE: Accumulating evidence suggests that cytochrome P450 (CYP) epoxygenases metabolize arachidonic acid into epoxyeicosatrienoic acids (EETs), which play crucial and diverse roles in cardiovascular homeostasis. The anti-inflammatory, antihypertensive, and pro-proliferative effects of EETs sugg...
Autores principales: | Xu, Xizhen, Zhao, Chun Xia, Wang, Luyun, Tu, Ling, Fang, Xiaosai, Zheng, Changlong, Edin, Matthew L., Zeldin, Darryl C., Wang, Dao Wen |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844847/ https://www.ncbi.nlm.nih.gov/pubmed/20068141 http://dx.doi.org/10.2337/db09-1241 |
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