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SoDA2: a Hidden Markov Model approach for identification of immunoglobulin rearrangements
Motivation: The inference of pre-mutation immunoglobulin (Ig) rearrangements is essential in the study of the antibody repertoires produced in response to infection, in B-cell neoplasms and in autoimmune disease. Often, there are several rearrangements that are nearly equivalent as candidates for a...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844993/ https://www.ncbi.nlm.nih.gov/pubmed/20147303 http://dx.doi.org/10.1093/bioinformatics/btq056 |