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Focal adhesions are sites of integrin extension

Integrins undergo global conformational changes that specify their activation state. Current models portray the inactive receptor in a bent conformation that upon activation converts to a fully extended form in which the integrin subunit leg regions are separated to enable ligand binding and subsequ...

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Detalles Bibliográficos
Autores principales:	Askari, Janet A., Tynan, Christopher J., Webb, Stephen E.D., Martin-Fernandez, Marisa L., Ballestrem, Christoph, Humphries, Martin J.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2010
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845069/ https://www.ncbi.nlm.nih.gov/pubmed/20231384 http://dx.doi.org/10.1083/jcb.200907174

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