The Arf tumor suppressor protein inhibits Miz1 to suppress cell adhesion and induce apoptosis

Oncogenic stress induces expression of the alternate reading frame (Arf) tumor suppressor protein. Arf then stabilizes p53, which leads to cell cycle arrest or apoptosis. The mechanisms that distinguish both outcomes are incompletely understood. In this study, we show that Arf interacts with the Myc...

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Detalles Bibliográficos
Autores principales: Herkert, Barbara, Dwertmann, Anne, Herold, Steffi, Abed, Mona, Naud, Jean-Francois, Finkernagel, Florian, Harms, Gregory S., Orian, Amir, Wanzel, Michael, Eilers, Martin
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845071/
https://www.ncbi.nlm.nih.gov/pubmed/20308430
http://dx.doi.org/10.1083/jcb.200908103

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