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Inner centromere formation requires hMis14, a trident kinetochore protein that specifically recruits HP1 to human chromosomes
Centromeric DNA forms two structures on the mitotic chromosome: the kinetochore, which interacts with kinetochore microtubules, and the inner centromere, which connects sister kinetochores. The assembly of the inner centromere is poorly understood. In this study, we show that the human Mis14 (hMis14...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845078/ https://www.ncbi.nlm.nih.gov/pubmed/20231385 http://dx.doi.org/10.1083/jcb.200908096 |