ERO1-β, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis

Mostrar otras versiones (1)

Mammals have two genes encoding homologues of the endoplasmic reticulum (ER) disulfide oxidase ERO1 (ER oxidoreductin 1). ERO1-β is greatly enriched in the endocrine pancreas. We report in this study that homozygosity for a disrupting allele of Ero1lb selectively compromises oxidative folding of pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Zito, Ester, Chin, King-Tung, Blais, Jaime, Harding, Heather P., Ron, David
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845084/
https://www.ncbi.nlm.nih.gov/pubmed/20308425
http://dx.doi.org/10.1083/jcb.200911086

Ejemplares similares

Ejemplares similares