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Mild folate deficiency induces genetic and epigenetic instability and phenotype changes in prostate cancer cells

BACKGROUND: Folate (vitamin B9) is essential for cellular proliferation as it is involved in the biosynthesis of deoxythymidine monophosphate (dTMP) and s-adenosylmethionine (AdoMet). The link between folate depletion and the genesis and progression of cancers of epithelial origin is of high clinica...

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Detalles Bibliográficos
Autores principales:	Bistulfi, Gaia, VanDette, Erika, Matsui, Sei-Ichi, Smiraglia, Dominic J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845099/ https://www.ncbi.nlm.nih.gov/pubmed/20092614 http://dx.doi.org/10.1186/1741-7007-8-6

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