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The molecular basis of beta-thalassemia intermedia in southern China: genotypic heterogeneity and phenotypic diversity

BACKGROUND: The clinical syndrome of thalassemia intermedia (TI) results from the β-globin genotypes in combination with factors to produce fetal haemoglobin (HbF) and/or co-inheritance of α-thalassemia. However, very little is currently known of the molecular basis of Chinese TI patients. METHODS:...

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Detalles Bibliográficos
Autores principales: Chen, Wanqun, Zhang, Xinhua, Shang, Xuan, Cai, Ren, Li, Liyan, Zhou, Tianhong, Sun, Manna, Xiong, Fu, Xu, Xiangmin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845123/
https://www.ncbi.nlm.nih.gov/pubmed/20181291
http://dx.doi.org/10.1186/1471-2350-11-31

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