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Tousled kinase TLK1B mediates chromatin assembly in conjunction with Asf1 regardless of its kinase activity
BACKGROUND: The Tousled Like Kinases (TLKs) are involved in chromatin dynamics, including DNA replication and repair, transcription, and chromosome segregation. Indeed, the first two TLK1 substrates were identified as the histone H3 and Asf1 (a histone H3/H4 chaperone), which immediately suggested a...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845150/ https://www.ncbi.nlm.nih.gov/pubmed/20222959 http://dx.doi.org/10.1186/1756-0500-3-68 |