Cargando…
A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome
Bioinformatic analysis classifies the human protein encoded by immature colon carcinoma transcript-1 (ICT1) as one of a family of four putative mitochondrial translation release factors. However, this has not been supported by any experimental evidence. As only a single member of this family, mtRF1a...
Autores principales: | Richter, Ricarda, Rorbach, Joanna, Pajak, Aleksandra, Smith, Paul M, Wessels, Hans J, Huynen, Martijn A, Smeitink, Jan A, Lightowlers, Robert N, Chrzanowska-Lightowlers, Zofia M |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845271/ https://www.ncbi.nlm.nih.gov/pubmed/20186120 http://dx.doi.org/10.1038/emboj.2010.14 |
Ejemplares similares
-
Interactions between peptidyl tRNA hydrolase homologs and the ribosomal release factor Mrf1 in S. pombe mitochondria
por: Dujeancourt, Laurent, et al.
Publicado: (2013) -
Response to “Ribosome Rescue and Translation Termination at Non-standard Stop Codons by ICT1 in Mammalian Mitochondria”
por: Chrzanowska-Lightowlers, Zofia Maria, et al.
Publicado: (2015) -
The human mitochondrial ribosome recycling factor is essential for cell viability
por: Rorbach, Joanna, et al.
Publicado: (2008) -
The human RNA-binding protein RBFA promotes the maturation of the mitochondrial ribosome
por: Rozanska, Agata, et al.
Publicado: (2017) -
Human mitochondrial ribosomes can switch structural tRNAs – but when and why?
por: Chrzanowska-Lightowlers, Zofia, et al.
Publicado: (2017)