Anti-viral state segregates two molecular phenotypes of pancreatic adenocarcinoma: potential relevance for adenoviral gene therapy

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) remains a leading cause of cancer mortality for which novel gene therapy approaches relying on tumor-tropic adenoviruses are being tested. METHODS: We obtained the global transcriptional profiling of primary PDAC using RNA from eight xenografted pr...

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Detalles Bibliográficos
Autores principales: Monsurrò, Vladia, Beghelli, Stefania, Wang, Richard, Barbi, Stefano, Coin, Silvia, Di Pasquale, Giovanni, Bersani, Samantha, Castellucci, Monica, Sorio, Claudio, Eleuteri, Stefano, Worschech, Andrea, Chiorini, Jay A, Pederzoli, Paolo, Alter, Harvey, Marincola, Francesco M, Scarpa, Aldo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845551/
https://www.ncbi.nlm.nih.gov/pubmed/20113473
http://dx.doi.org/10.1186/1479-5876-8-10

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