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Genome-Wide Association Study Identifies GPC5 as a Novel Genetic Locus Protective against Sudden Cardiac Arrest

BACKGROUND: Existing studies indicate a significant genetic component for sudden cardiac arrest (SCA) and genome-wide association studies (GWAS) provide an unbiased approach for identification of novel genes. We performed a GWAS to identify genetic determinants of SCA. METHODOLOGY/PRINCIPAL FINDINGS...

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Detalles Bibliográficos
Autores principales: Arking, Dan E., Reinier, Kyndaron, Post, Wendy, Jui, Jonathan, Hilton, Gina, O'Connor, Ashley, Prineas, Ronald J., Boerwinkle, Eric, Psaty, Bruce M., Tomaselli, Gordon F., Rea, Thomas, Sotoodehnia, Nona, Siscovick, David S., Burke, Gregory L., Marban, Eduardo, Spooner, Peter M., Chakravarti, Aravinda, Chugh, Sumeet S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845611/
https://www.ncbi.nlm.nih.gov/pubmed/20360844
http://dx.doi.org/10.1371/journal.pone.0009879

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