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Genome-Wide Association Study Identifies GPC5 as a Novel Genetic Locus Protective against Sudden Cardiac Arrest
BACKGROUND: Existing studies indicate a significant genetic component for sudden cardiac arrest (SCA) and genome-wide association studies (GWAS) provide an unbiased approach for identification of novel genes. We performed a GWAS to identify genetic determinants of SCA. METHODOLOGY/PRINCIPAL FINDINGS...
Autores principales: | Arking, Dan E., Reinier, Kyndaron, Post, Wendy, Jui, Jonathan, Hilton, Gina, O'Connor, Ashley, Prineas, Ronald J., Boerwinkle, Eric, Psaty, Bruce M., Tomaselli, Gordon F., Rea, Thomas, Sotoodehnia, Nona, Siscovick, David S., Burke, Gregory L., Marban, Eduardo, Spooner, Peter M., Chakravarti, Aravinda, Chugh, Sumeet S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845611/ https://www.ncbi.nlm.nih.gov/pubmed/20360844 http://dx.doi.org/10.1371/journal.pone.0009879 |
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