Exoerythrocytic Plasmodium Parasites Secrete a Cysteine Protease Inhibitor Involved in Sporozoite Invasion and Capable of Blocking Cell Death of Host Hepatocytes

Plasmodium parasites must control cysteine protease activity that is critical for hepatocyte invasion by sporozoites, liver stage development, host cell survival and merozoite liberation. Here we show that exoerythrocytic P. berghei parasites express a potent cysteine protease inhibitor (PbICP, P. b...

Descripción completa

Detalles Bibliográficos
Autores principales: Rennenberg, Annika, Lehmann, Christine, Heitmann, Anna, Witt, Tina, Hansen, Guido, Nagarajan, Krishna, Deschermeier, Christina, Turk, Vito, Hilgenfeld, Rolf, Heussler, Volker T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845656/
https://www.ncbi.nlm.nih.gov/pubmed/20361051
http://dx.doi.org/10.1371/journal.ppat.1000825

Ejemplares similares

Ejemplares similares