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Inhibition of Macrophage Migration Inhibitory Factor Ameliorates Ocular Pseudomonas aeruginosa-Induced Keratitis
Pseudomonas aeruginosa causes severe sight-threatening corneal infections, with the inflammatory response to the pathogen being the major factor resulting in damage to the cornea that leads to loss of visual acuity. We found that mice deficient for macrophage migration inhibitory factor (MIF), a key...
Autores principales: | Gadjeva, Mihaela, Nagashima, Jill, Zaidi, Tanweer, Mitchell, Robert A., Pier, Gerald B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845658/ https://www.ncbi.nlm.nih.gov/pubmed/20361053 http://dx.doi.org/10.1371/journal.ppat.1000826 |
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