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Srs2: The “Odd-Job Man” in DNA repair
Homologous recombination plays a key role in the maintenance of genome integrity, especially during DNA replication and the repair of double-stranded DNA breaks (DSBs). Just a single un-repaired break can lead to aneuploidy, genetic aberrations or cell death. DSBs are caused by a vast number of both...
Autores principales: | Marini, Victoria, Krejci, Lumir |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845805/ https://www.ncbi.nlm.nih.gov/pubmed/20096651 http://dx.doi.org/10.1016/j.dnarep.2010.01.007 |
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