SKAP1 is dispensable for chemokine-induced migration of primary T-cells

Immune adaptors SLP-76, ADAP and SKAP1 (SKAP-55) play central roles in anti-CD3 induced ‘inside-out’ signalling for LFA-1 activation and ICAM-1 adhesion. However, it has been unclear whether SKAP1 is also required for chemokine-induced T-cell motility. In this study, we found that SDF-1 and CCL21 in...

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Detalles Bibliográficos
Autores principales: Wang, Hongyan, Lu, Yuning, Rudd, Christopher E.
Formato: Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845813/
https://www.ncbi.nlm.nih.gov/pubmed/19883688
http://dx.doi.org/10.1016/j.imlet.2009.10.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845813/
https://www.ncbi.nlm.nih.gov/pubmed/19883688
http://dx.doi.org/10.1016/j.imlet.2009.10.010

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