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SKAP1 is dispensable for chemokine-induced migration of primary T-cells
Immune adaptors SLP-76, ADAP and SKAP1 (SKAP-55) play central roles in anti-CD3 induced ‘inside-out’ signalling for LFA-1 activation and ICAM-1 adhesion. However, it has been unclear whether SKAP1 is also required for chemokine-induced T-cell motility. In this study, we found that SDF-1 and CCL21 in...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier/North-Holland Biomedical Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845813/ https://www.ncbi.nlm.nih.gov/pubmed/19883688 http://dx.doi.org/10.1016/j.imlet.2009.10.010 |