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Anti-angiogenic tyrosine kinase inhibitors: what is their mechanism of action?
Tyrosine kinases are important cellular signaling proteins that have a variety of biological activities including cell proliferation and migration. Multiple kinases are involved in angiogenesis, including receptor tyrosine kinases such as the vascular endothelial growth factor receptor. Inhibition o...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Springer Netherlands
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845892/ https://www.ncbi.nlm.nih.gov/pubmed/20012482 http://dx.doi.org/10.1007/s10456-009-9160-6 |