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Advantages of Intranasal Vaccination and Considerations on Device Selection

Oral and Intramuscular vaccination has been considered till date as the ultimate ways, but nasal route offers advantages such as ease of self administration and induction of mucosal as well as systemic immunity. Both liquid and dry powder formulations can be given via intranasal route. A great consi...

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Detalles Bibliográficos
Autores principales: Birkhoff, M., Leitz, M., Marx, D.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846493/
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author Birkhoff, M.
Leitz, M.
Marx, D.
author_facet Birkhoff, M.
Leitz, M.
Marx, D.
author_sort Birkhoff, M.
collection PubMed
description Oral and Intramuscular vaccination has been considered till date as the ultimate ways, but nasal route offers advantages such as ease of self administration and induction of mucosal as well as systemic immunity. Both liquid and dry powder formulations can be given via intranasal route. A great consideration has to be given while selecting a suitable device for nasal administration since the volume delivered is very low. A number of devices are available based on number of doses to be administered and type of dosage formulation.
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spelling pubmed-28464932010-04-06 Advantages of Intranasal Vaccination and Considerations on Device Selection Birkhoff, M. Leitz, M. Marx, D. Indian J Pharm Sci Abstract Oral and Intramuscular vaccination has been considered till date as the ultimate ways, but nasal route offers advantages such as ease of self administration and induction of mucosal as well as systemic immunity. Both liquid and dry powder formulations can be given via intranasal route. A great consideration has to be given while selecting a suitable device for nasal administration since the volume delivered is very low. A number of devices are available based on number of doses to be administered and type of dosage formulation. Medknow Publications 2009 /pmc/articles/PMC2846493/ Text en © Indian Journal of Pharmaceutical Sciences http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstract
Birkhoff, M.
Leitz, M.
Marx, D.
Advantages of Intranasal Vaccination and Considerations on Device Selection
title Advantages of Intranasal Vaccination and Considerations on Device Selection
title_full Advantages of Intranasal Vaccination and Considerations on Device Selection
title_fullStr Advantages of Intranasal Vaccination and Considerations on Device Selection
title_full_unstemmed Advantages of Intranasal Vaccination and Considerations on Device Selection
title_short Advantages of Intranasal Vaccination and Considerations on Device Selection
title_sort advantages of intranasal vaccination and considerations on device selection
topic Abstract
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846493/
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