Synaptotagmin-IV Modulates Synaptic Function and LTP by Regulating BDNF Release

Synaptotagmin-IV (syt-IV) is a membrane trafficking protein that influences learning and memory, but its localization and role in synaptic function remain unclear. Here we discovered that syt-IV localizes to BDNF-containing vesicles in hippocampal neurons. Syt-IV/BDNF-harboring vesicles undergo exoc...

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Detalles Bibliográficos
Autores principales: Dean, Camin, Liu, Huisheng, Dunning, F. Mark, Chang, Payne Y., Jackson, Meyer B., Chapman, Edwin R.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846764/
https://www.ncbi.nlm.nih.gov/pubmed/19448629
http://dx.doi.org/10.1038/nn.2315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846764/
https://www.ncbi.nlm.nih.gov/pubmed/19448629
http://dx.doi.org/10.1038/nn.2315

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