Cargando…
Need-Based Up-Regulation of Protein Levels in Response to Deletion of Their Duplicate Genes
Many duplicate genes maintain functional overlap despite divergence over long evolutionary time scales. Deleting one member of a paralogous pair often has no phenotypic effect, unless its paralog is also deleted. It has been suggested that this functional compensation might be mediated by active up-...
Autores principales: | DeLuna, Alexander, Springer, Michael, Kirschner, Marc W., Kishony, Roy |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846854/ https://www.ncbi.nlm.nih.gov/pubmed/20361019 http://dx.doi.org/10.1371/journal.pbio.1000347 |
Ejemplares similares
-
Gene duplication and the evolution of moonlighting proteins
por: Espinosa-Cantú, Adriana, et al.
Publicado: (2015) -
Increased rates of protein evolution and asymmetric deceleration after the whole-genome duplication in yeasts
por: Ascencio, Diana, et al.
Publicado: (2017) -
Expression attenuation as a mechanism of robustness against gene duplication
por: Ascencio, Diana, et al.
Publicado: (2021) -
A competitive trade-off limits the selective advantage of increased antibiotic production
por: Gerardin, Ylaine, et al.
Publicado: (2016) -
Breakpoint mapping of 13 large parkin deletions/duplications reveals an exon 4 deletion and an exon 7 duplication as founder mutations
por: Elfferich, Peter, et al.
Publicado: (2011)