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Can Animal Models of Disease Reliably Inform Human Studies?

H. Bart van der Worp and colleagues discuss the controversies and possibilities of translating the results of animal experiments into human clinical trials.

Detalles Bibliográficos
Autores principales: van der Worp, H. Bart, Howells, David W., Sena, Emily S., Porritt, Michelle J., Rewell, Sarah, O'Collins, Victoria, Macleod, Malcolm R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846855/
https://www.ncbi.nlm.nih.gov/pubmed/20361020
http://dx.doi.org/10.1371/journal.pmed.1000245
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author van der Worp, H. Bart
Howells, David W.
Sena, Emily S.
Porritt, Michelle J.
Rewell, Sarah
O'Collins, Victoria
Macleod, Malcolm R.
author_facet van der Worp, H. Bart
Howells, David W.
Sena, Emily S.
Porritt, Michelle J.
Rewell, Sarah
O'Collins, Victoria
Macleod, Malcolm R.
author_sort van der Worp, H. Bart
collection PubMed
description H. Bart van der Worp and colleagues discuss the controversies and possibilities of translating the results of animal experiments into human clinical trials.
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spelling pubmed-28468552010-04-02 Can Animal Models of Disease Reliably Inform Human Studies? van der Worp, H. Bart Howells, David W. Sena, Emily S. Porritt, Michelle J. Rewell, Sarah O'Collins, Victoria Macleod, Malcolm R. PLoS Med Research in Translation H. Bart van der Worp and colleagues discuss the controversies and possibilities of translating the results of animal experiments into human clinical trials. Public Library of Science 2010-03-30 /pmc/articles/PMC2846855/ /pubmed/20361020 http://dx.doi.org/10.1371/journal.pmed.1000245 Text en van der Worp et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research in Translation
van der Worp, H. Bart
Howells, David W.
Sena, Emily S.
Porritt, Michelle J.
Rewell, Sarah
O'Collins, Victoria
Macleod, Malcolm R.
Can Animal Models of Disease Reliably Inform Human Studies?
title Can Animal Models of Disease Reliably Inform Human Studies?
title_full Can Animal Models of Disease Reliably Inform Human Studies?
title_fullStr Can Animal Models of Disease Reliably Inform Human Studies?
title_full_unstemmed Can Animal Models of Disease Reliably Inform Human Studies?
title_short Can Animal Models of Disease Reliably Inform Human Studies?
title_sort can animal models of disease reliably inform human studies?
topic Research in Translation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846855/
https://www.ncbi.nlm.nih.gov/pubmed/20361020
http://dx.doi.org/10.1371/journal.pmed.1000245
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