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Tax gene expression and cell cycling but not cell death are selected during HTLV-1 infection in vivo
BACKGROUND: Adult T cell leukemia results from the malignant transformation of a CD4(+ )lymphoid clone carrying an integrated HTLV-1 provirus that has undergone several oncogenic events over a 30-60 year period of persistent clonal expansion. Both CD4(+ )and CD8(+ )lymphocytes are infected in vivo;...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846874/ https://www.ncbi.nlm.nih.gov/pubmed/20222966 http://dx.doi.org/10.1186/1742-4690-7-17 |