Tax gene expression and cell cycling but not cell death are selected during HTLV-1 infection in vivo

BACKGROUND: Adult T cell leukemia results from the malignant transformation of a CD4(+ )lymphoid clone carrying an integrated HTLV-1 provirus that has undergone several oncogenic events over a 30-60 year period of persistent clonal expansion. Both CD4(+ )and CD8(+ )lymphocytes are infected in vivo;...

Descripción completa

Detalles Bibliográficos
Autores principales: Zane, Linda, Sibon, David, Jeannin, Lionel, Zandecki, Marc, Delfau-Larue, Marie-Hélène, Gessain, Antoine, Gout, Olivier, Pinatel, Christiane, Lançon, Agnès, Mortreux, Franck, Wattel, Eric
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846874/
https://www.ncbi.nlm.nih.gov/pubmed/20222966
http://dx.doi.org/10.1186/1742-4690-7-17

Ejemplares similares

Ejemplares similares