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Mechanisms of tumor necrosis factor-α-induced interleukin-6 synthesis in glioma cells

BACKGROUND: Interleukin (IL)-6 plays a pivotal role in a variety of CNS functions such as the induction and modulation of reactive astrogliosis, pathological inflammatory responses and neuroprotection. Tumor necrosis factor (TNF)-α induces IL-6 release from rat C6 glioma cells through the inhibitory...

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Detalles Bibliográficos
Autores principales: Tanabe, Kumiko, Matsushima-Nishiwaki, Rie, Yamaguchi, Shinobu, Iida, Hiroki, Dohi, Shuji, Kozawa, Osamu
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846903/
https://www.ncbi.nlm.nih.gov/pubmed/20205746
http://dx.doi.org/10.1186/1742-2094-7-16