A fast rod photoreceptor signaling pathway in the mammalian retina

Rod photoreceptors were recently shown to contact Off cone bipolar cells, providing a novel pathway for rod signal flow in the mammalian retina. By recording from pairs of rods and Off cone bipolar cells in the ground squirrel, we measured the synaptic responses of mammalian rods unfiltered by the s...

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Detalles Bibliográficos
Autores principales: Li, Wei, Chen, Shan, DeVries, Steven H.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847031/
https://www.ncbi.nlm.nih.gov/pubmed/20190742
http://dx.doi.org/10.1038/nn.2507
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author Li, Wei
Chen, Shan
DeVries, Steven H.
author_facet Li, Wei
Chen, Shan
DeVries, Steven H.
author_sort Li, Wei
collection PubMed
description Rod photoreceptors were recently shown to contact Off cone bipolar cells, providing a novel pathway for rod signal flow in the mammalian retina. By recording from pairs of rods and Off cone bipolar cells in the ground squirrel, we measured the synaptic responses of mammalian rods unfiltered by the slow kinetics of the rod bipolar cell response. We show that vesicle fusion and turnover in mammalian rods is fast, and that this new pathway can mediate rapid signaling.
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spelling pubmed-28470312010-10-01 A fast rod photoreceptor signaling pathway in the mammalian retina Li, Wei Chen, Shan DeVries, Steven H. Nat Neurosci Article Rod photoreceptors were recently shown to contact Off cone bipolar cells, providing a novel pathway for rod signal flow in the mammalian retina. By recording from pairs of rods and Off cone bipolar cells in the ground squirrel, we measured the synaptic responses of mammalian rods unfiltered by the slow kinetics of the rod bipolar cell response. We show that vesicle fusion and turnover in mammalian rods is fast, and that this new pathway can mediate rapid signaling. 2010-02-28 2010-04 /pmc/articles/PMC2847031/ /pubmed/20190742 http://dx.doi.org/10.1038/nn.2507 Text en Users may view, print, copy, download and text and data- mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Li, Wei
Chen, Shan
DeVries, Steven H.
A fast rod photoreceptor signaling pathway in the mammalian retina
title A fast rod photoreceptor signaling pathway in the mammalian retina
title_full A fast rod photoreceptor signaling pathway in the mammalian retina
title_fullStr A fast rod photoreceptor signaling pathway in the mammalian retina
title_full_unstemmed A fast rod photoreceptor signaling pathway in the mammalian retina
title_short A fast rod photoreceptor signaling pathway in the mammalian retina
title_sort fast rod photoreceptor signaling pathway in the mammalian retina
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847031/
https://www.ncbi.nlm.nih.gov/pubmed/20190742
http://dx.doi.org/10.1038/nn.2507
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