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Reduced hippocampal neurogenesis in the GR(+/−) genetic mouse model of depression

Glucocorticoid receptor (GR) heterozygous mice (GR(+/−)) represent a valuable animal model for major depression. GR(+/−) mice show a depression-related phenotype characterized by increased learned helplessness on the behavioral level and neuroendocrine alterations with hypothalamo-pituitary-adrenal...

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Detalles Bibliográficos
Autores principales: Kronenberg, Golo, Kirste, Imke, Inta, Dragos, Chourbaji, Sabine, Heuser, Isabella, Endres, Matthias, Gass, Peter
Formato: Texto
Lenguaje:English
Publicado: D. Steinkopff-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847168/
https://www.ncbi.nlm.nih.gov/pubmed/19644729
http://dx.doi.org/10.1007/s00406-009-0036-y