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Reduced hippocampal neurogenesis in the GR(+/−) genetic mouse model of depression
Glucocorticoid receptor (GR) heterozygous mice (GR(+/−)) represent a valuable animal model for major depression. GR(+/−) mice show a depression-related phenotype characterized by increased learned helplessness on the behavioral level and neuroendocrine alterations with hypothalamo-pituitary-adrenal...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
D. Steinkopff-Verlag
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847168/ https://www.ncbi.nlm.nih.gov/pubmed/19644729 http://dx.doi.org/10.1007/s00406-009-0036-y |