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GoLoco motif proteins binding to Gα(i1): insights from molecular simulations
Molecular dynamics simulations, computational alanine scanning and sequence analysis were used to investigate the structural properties of the Gα(i1)/GoLoco peptide complex. Using these methodologies, binding of the GoLoco motif peptide to the Gα(i1) subunit was found to restrict the relative moveme...
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| Formato: | Texto |
| Lenguaje: | English |
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Springer-Verlag
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847169/ https://www.ncbi.nlm.nih.gov/pubmed/19437048 http://dx.doi.org/10.1007/s00894-009-0516-z |