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The multi-domain protein Np95 connects DNA methylation and histone modification

DNA methylation and histone modifications play a central role in the epigenetic regulation of gene expression and cell differentiation. Recently, Np95 (also known as UHRF1 or ICBP90) has been found to interact with Dnmt1 and to bind hemimethylated DNA, indicating together with genetic studies a cent...

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Detalles Bibliográficos
Autores principales:	Rottach, Andrea, Frauer, Carina, Pichler, Garwin, Bonapace, Ian Marc, Spada, Fabio, Leonhardt, Heinrich
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847221/ https://www.ncbi.nlm.nih.gov/pubmed/20026581 http://dx.doi.org/10.1093/nar/gkp1152

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