Definition of the interacting interfaces of Apobec3G and HIV-1 Vif using MAPPIT mutagenesis analysis

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The host restriction factor Apobec3G is a cytidine deaminase that incorporates into HIV-1 virions and interferes with viral replication. The HIV-1 accessory protein Vif subverts Apobec3G by targeting it for proteasomal degradation. We propose a model in which Apobec3G N-terminal domains symmetricall...

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Detalles Bibliográficos
Autores principales: Lavens, Delphine, Peelman, Frank, Van der Heyden, José, Uyttendaele, Isabel, Catteeuw, Dominiek, Verhee, Annick, Van Schoubroeck, Bertrand, Kurth, Julia, Hallenberger, Sabine, Clayton, Reginald, Tavernier, Jan
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847223/
https://www.ncbi.nlm.nih.gov/pubmed/20015971
http://dx.doi.org/10.1093/nar/gkp1154
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