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PCRPi: Presaging Critical Residues in Protein interfaces, a new computational tool to chart hot spots in protein interfaces

Protein–protein interactions (PPIs) are ubiquitous in Biology, and thus offer an enormous potential for the discovery of novel therapeutics. Although protein interfaces are large and lack defining physiochemical traits, is well established that only a small portion of interface residues, the so-call...

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Detalles Bibliográficos
Autores principales: Assi, Salam A., Tanaka, Tomoyuki, Rabbitts, Terence H., Fernandez-Fuentes, Narcis
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847225/
https://www.ncbi.nlm.nih.gov/pubmed/20008102
http://dx.doi.org/10.1093/nar/gkp1158