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Control of directionality in the DNA strand-exchange reaction catalysed by the tyrosine recombinase TnpI

In DNA site-specific recombination catalysed by tyrosine recombinases, two pairs of DNA strands are sequentially exchanged between separate duplexes and the mechanisms that confer directionality to this theoretically reversible reaction remain unclear. The tyrosine recombinase TnpI acts at the inter...

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Detalles Bibliográficos
Autores principales: Vanhooff, Virginie, Normand, Christophe, Galloy, Christine, Segall, Anca M., Hallet, Bernard
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847244/
https://www.ncbi.nlm.nih.gov/pubmed/20044348
http://dx.doi.org/10.1093/nar/gkp1187