Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/β-catenin targets

Alternative splicing can produce multiple protein products with variable domain composition from a single gene. The mouse Tcf7l2 gene is subject to alternative splicing. It encodes TCF4, a member of the T-cell factor (TCF) family of DNA-binding proteins and a nuclear interaction partner of β-catenin...

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Detalles Bibliográficos
Autores principales: Weise, Andreas, Bruser, Katja, Elfert, Susanne, Wallmen, Britta, Wittel, Yvonne, Wöhrle, Simon, Hecht, Andreas
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847248/
https://www.ncbi.nlm.nih.gov/pubmed/20044351
http://dx.doi.org/10.1093/nar/gkp1197

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