Mph1 requires mismatch repair-independent and -dependent functions of MutSα to regulate crossover formation during homologous recombination repair

In budding yeast the DNA helicase Mph1 prevents genome rearrangements during ectopic homologous recombination (HR) by suppressing the formation of crossovers (COs). Here we show that during ectopic HR repair, the anti-CO function of Mph1 is intricately associated with the mismatch repair (MMR) facto...

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Detalles Bibliográficos
Autores principales: Tay, Ye Dee, Sidebotham, Julie M., Wu, Leonard
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847250/
https://www.ncbi.nlm.nih.gov/pubmed/20047969
http://dx.doi.org/10.1093/nar/gkp1199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847250/
https://www.ncbi.nlm.nih.gov/pubmed/20047969
http://dx.doi.org/10.1093/nar/gkp1199

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