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Delayed Resolution of Acute Inflammation in Ulcerative Colitis Is Associated with Elevated Cytokine Release Downstream of TLR4

BACKGROUND: Ulcerative colitis (UC) is widely viewed as a leukocyte-mediated disorder. Although strong evidence implicates an exuberant response to microbial components in its pathogenesis, no intrinsic immune defect has been identified and the underlying pathogenic mechanisms remain obscure. METHOD...

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Detalles Bibliográficos
Autores principales: Rahman, Farooq Z., Smith, Andrew M., Hayee, Bu'Hussain, Marks, Daniel J. B., Bloom, Stuart L., Segal, Anthony W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847519/
https://www.ncbi.nlm.nih.gov/pubmed/20360984
http://dx.doi.org/10.1371/journal.pone.0009891

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