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Delayed Resolution of Acute Inflammation in Ulcerative Colitis Is Associated with Elevated Cytokine Release Downstream of TLR4
BACKGROUND: Ulcerative colitis (UC) is widely viewed as a leukocyte-mediated disorder. Although strong evidence implicates an exuberant response to microbial components in its pathogenesis, no intrinsic immune defect has been identified and the underlying pathogenic mechanisms remain obscure. METHOD...
Autores principales: | Rahman, Farooq Z., Smith, Andrew M., Hayee, Bu'Hussain, Marks, Daniel J. B., Bloom, Stuart L., Segal, Anthony W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847519/ https://www.ncbi.nlm.nih.gov/pubmed/20360984 http://dx.doi.org/10.1371/journal.pone.0009891 |
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