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Betacellulin inhibits osteogenic differentiation and stimulates proliferation through HIF-1α
Cellular signaling via epidermal growth factor (EGF) and EGF-like ligands can determine cell fate and behavior. Osteoblasts, which are responsible for forming and mineralizing osteoid, express EGF receptors and alter rates of proliferation and differentiation in response to EGF receptor activation....
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847694/ https://www.ncbi.nlm.nih.gov/pubmed/20165885 http://dx.doi.org/10.1007/s00441-010-0929-0 |