Dietary, lifestyle and clinicopathological factors associated with BRAF and K-ras mutations arising in distinct subsets of colorectal cancers in the EPIC Norfolk study

BACKGROUND: BRAF and K-ras proto-oncogenes encode components of the ERK signalling pathway and are frequently mutated in colorectal cancer. This study investigates the associations between BRAF and K-ras mutations and clinicopathological, lifestyle and dietary factors in colorectal cancers. METHODS:...

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Detalles Bibliográficos
Autores principales: Naguib, Adam, Mitrou, Panagiota N, Gay, Laura J, Cooke, James C, Luben, Robert N, Ball, Richard Y, McTaggart, Alison, Arends, Mark J, Rodwell, Sheila A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847960/
https://www.ncbi.nlm.nih.gov/pubmed/20233436
http://dx.doi.org/10.1186/1471-2407-10-99

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