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Transformation of SV40-immortalized human uroepithelial cells by 3-methylcholanthrene increases IFN- and Large T Antigen-induced transcripts

BACKGROUND: Simian Virus 40 (SV40) immortalization followed by treatment of cells with 3-methylcholanthrene (3-MC) has been used to elicit tumors in athymic mice. 3-MC carcinogenesis has been thoroughly studied, however gene-level interactions between 3-MC and SV40 that could have produced the obser...

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Detalles Bibliográficos
Autores principales:	Crosby, Lynn M, Moore, Tanya M, George, Michael, Yoon, Lawrence W, Easton, Marilyn J, Ni, Hong, Morgan, Kevin T, DeAngelo, Anthony B
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Primary research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848030/ https://www.ncbi.nlm.nih.gov/pubmed/20178601 http://dx.doi.org/10.1186/1475-2867-10-4

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