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Cytosolic group IVa phospholipase A(2 )mediates IL-8/CXCL8-induced transmigration of human polymorphonuclear leukocytes in vitro

BACKGROUND: Cytosolic gIVaPLA(2 )is a critical enzyme in the generation of arachidonate metabolites and in induction of β(2)-integrin adhesion in granulocytes. We hypothesized that gIVaPLA(2 )activation also is an essential downstream step for post adhesive migration of PMN in vitro. METHODS: Migrat...

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Detalles Bibliográficos
Autores principales:	Meliton, Angelo Y, Muñoz, Nilda M, Meliton, Lucille N, Binder, David C, Osan, Christopher M, Zhu, Xiangdong, Dudek, Steven M, Leff, Alan R
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848033/ https://www.ncbi.nlm.nih.gov/pubmed/20298597 http://dx.doi.org/10.1186/1476-9255-7-14

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