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AMPK exerts dual regulatory effects on the PI3K pathway

BACKGROUND: AMP-activated protein kinase (AMPK) is a fuel-sensing enzyme that is activated when cells experience energy deficiency and conversely suppressed in surfeit of energy supply. AMPK activation improves insulin sensitivity via multiple mechanisms, among which AMPK suppresses mTOR/S6K-mediate...

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Detalles Bibliográficos
Autores principales:	Tao, Rong, Gong, Jun, Luo, Xixi, Zang, Mengwei, Guo, Wen, Wen, Rong, Luo, Zhijun
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848036/ https://www.ncbi.nlm.nih.gov/pubmed/20167101 http://dx.doi.org/10.1186/1750-2187-5-1

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