Cargando…

Dynamics of pfcrt alleles CVMNK and CVIET in chloroquine-treated Sudanese patients infected with Plasmodium falciparum

BACKGROUND: Parasite resistance to the anti-malarial drug chloroquine is common in eastern Sudan. Dynamic within-host changes in the relative abundance of both sensitive and resistant Plasmodium falciparum parasites were examined in a cohort of chloroquine-treated patients presenting with uncomplica...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gadalla, Nahla B, Elzaki, Salah Eldin, Mukhtar, Ebtihal, Warhurst, David C, El-Sayed, Badria, Sutherland, Colin J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848148/ https://www.ncbi.nlm.nih.gov/pubmed/20226032 http://dx.doi.org/10.1186/1475-2875-9-74

Ejemplares similares

Alternatively spliced transcripts and novel pseudogenes of the Plasmodium falciparum resistance-associated locus pfcrt detected in East African malaria patients
por: Gadalla, Nahla B., et al.
Publicado: (2015)

High prevalence of pfcrt-CVIET haplotype in isolates from asymptomatic and symptomatic patients in south-central Oromia, Ethiopia
por: Golassa, Lemu, et al.
Publicado: (2014)

A comparative study on the efficacy of artesunate plus sulphadoxine/pyrimethamine versus artemether-lumefantrine in eastern Sudan
por: Mukhtar, Ebtihal A, et al.
Publicado: (2007)

Low Prevalence of Pfcrt Resistance Alleles among Patients with Uncomplicated Falciparum Malaria in Niger Six Years after Chloroquine Withdrawal
por: Salissou, Adamou, et al.
Publicado: (2014)

Assessment of the Molecular Marker of Plasmodium falciparum Chloroquine Resistance (Pfcrt) in Senegal after Several Years of Chloroquine Withdrawal
por: Ndiaye, Magatte, et al.
Publicado: (2012)

Identification of a Mutant PfCRT-Mediated Chloroquine Tolerance Phenotype in Plasmodium falciparum
por: Valderramos, Stephanie G., et al.
Publicado: (2010)

Large-scale survey for novel genotypes of Plasmodium falciparum chloroquine-resistance gene pfcrt
por: Takahashi, Nobuyuki, et al.
Publicado: (2012)

Reemergence of chloroquine-sensitive pfcrt K76 Plasmodium falciparum genotype in southeastern Cameroon
por: Ndam, Nicaise Tuikue, et al.
Publicado: (2017)

Distribution of pfmdr1 and pfcrt chloroquine drug resistance alleles in north-western Nigeria
por: Muhammad, Ruqayyah H., et al.
Publicado: (2017)

Chloroquine Clinical Failures in P. falciparum Malaria Are Associated with Mutant Pfmdr-1, Not Pfcrt in Madagascar
por: Andriantsoanirina, Valérie, et al.
Publicado: (2010)

The Knock-Down of the Chloroquine Resistance Transporter PfCRT Is Linked to Oligopeptide Handling in Plasmodium falciparum
por: Sanchez, Cecilia P., et al.
Publicado: (2022)

Polymorphism in the Plasmodium falciparum chloroquine-resistance transporter protein links verapamil enhancement of chloroquine sensitivity with the clinical efficacy of amodiaquine
por: Warhurst, David C
Publicado: (2003)

A Randomized Open-Label Trial of Artesunate- Sulfadoxine-Pyrimethamine with or without Primaquine for Elimination of Sub-Microscopic P. falciparum Parasitaemia and Gametocyte Carriage in Eastern Sudan
por: El-Sayed, Badria, et al.
Publicado: (2007)

Sequence and gene expression of chloroquine resistance transporter (pfcrt) in the association of in vitro drugs resistance of Plasmodium falciparum
por: Chaijaroenkul, Wanna, et al.
Publicado: (2011)

Investigation of the Plasmodium falciparum Food Vacuole through Inducible Expression of the Chloroquine Resistance Transporter (PfCRT)
por: Ehlgen, Florian, et al.
Publicado: (2012)

Functional Characterization of the Plasmodium falciparum Chloroquine-Resistance Transporter (PfCRT) in Transformed Dictyostelium discoideum Vesicles
por: Papakrivos, Janni, et al.
Publicado: (2012)

Genetic polymorphisms in Plasmodium falciparum chloroquine resistance genes, pfcrt and pfmdr1, in North Sulawesi, Indonesia
por: Reteng, Patrick, et al.
Publicado: (2017)

Dynamic of plasmodium falciparum chloroquine resistance transporter gene Pfcrt K76T mutation five years after withdrawal of chloroquine in Burkina Faso
por: Sondo, Paul, et al.
Publicado: (2015)

Evidence for linkage of pfmdr1, pfcrt, and pfk13 polymorphisms to lumefantrine and mefloquine susceptibilities in a Plasmodium falciparum cross
por: Windle, Sean T., et al.
Publicado: (2020)

Diversity of Plasmodium falciparum Chloroquine Resistance Transporter (pfcrt) Exon 2 Haplotypes in the Pacific from 1959 to 1979
por: Chan, Chim W., et al.
Publicado: (2012)

Plasmodium falciparum Chloroquine-pfcrt Resistant Haplotypes in Brazilian Endemic Areas Four Decades after CQ Withdrawn
por: de Abreu-Fernandes, Rebecca, et al.
Publicado: (2023)

Microsatellite polymorphism within pfcrt provides evidence of continuing evolution of chloroquine-resistant alleles in Papua New Guinea
por: DaRe, Jeana T, et al.
Publicado: (2007)

Directional Selection at the pfmdr1, pfcrt, pfubp1, and pfap2mu Loci of Plasmodium falciparum in Kenyan Children Treated With ACT
por: Henriques, Gisela, et al.
Publicado: (2014)

Sequence analysis of pfcrt and pfmdr1 genes and its association with chloroquine resistance in Southeast Indian Plasmodium falciparum isolates
por: Antony, Hiasindh Ashmi, et al.
Publicado: (2016)

Plasmodium falciparum chloroquine resistance transporter (PfCRT) isoforms PH1 and PH2 perturb vacuolar physiology
por: Callaghan, Paul S., et al.
Publicado: (2016)

Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, enlarge the parasite’s food vacuole and alter drug sensitivities
por: Pulcini, Serena, et al.
Publicado: (2015)

Prevalence of Plasmodium falciparum anti-malarial resistance-associated polymorphisms in pfcrt, pfmdr1 and pfnhe1 in Muheza, Tanzania, prior to introduction of artemisinin combination therapy
por: Gadalla, Nahla B, et al.
Publicado: (2015)

Trends in chloroquine resistance marker, Pfcrt-K76T mutation ten years after chloroquine withdrawal in Tanzania
por: Mohammed, Asia, et al.
Publicado: (2013)

Selection of pfdhfr/pfdhps alleles and declining artesunate/sulphadoxine-pyrimethamine efficacy against Plasmodium falciparum eight years after deployment in eastern Sudan
por: Gadalla, Nahla B, et al.
Publicado: (2013)

Chloroquine sensitivity: diminished prevalence of chloroquine-resistant gene marker pfcrt-76 13 years after cessation of chloroquine use in Msambweni, Kenya
por: Kiarie, William Chege, et al.
Publicado: (2015)

Rapid detection of Pfcrt and Pfmdr1 mutations in Plasmodium falciparum isolates by FRET and in vivo response to chloroquine among children from Osogbo, Nigeria
por: Ojurongbe, Olusola, et al.
Publicado: (2007)

High frequency of Plasmodium falciparum chloroquine resistance marker (pfcrt T76 mutation) in Yemen: An urgent need to re-examine malaria drug policy
por: Al-Mekhlafi, Abdulsalam M, et al.
Publicado: (2011)

The Role of Pfmdr1 and Pfcrt in Changing Chloroquine, Amodiaquine, Mefloquine and Lumefantrine Susceptibility in Western-Kenya P. falciparum Samples during 2008–2011
por: Eyase, Fredrick L., et al.
Publicado: (2013)

Prevalence of mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, and association with ex vivo susceptibility to common anti-malarial drugs against African Plasmodium falciparum isolates
por: Foguim, Francis Tsombeng, et al.
Publicado: (2020)

Prevalence of Plasmodium falciparum Pfcrt and Pfmdr1 alleles in settings with different levels of Plasmodium vivax co-endemicity in Ethiopia
por: Hailemeskel, Elifaged, et al.
Publicado: (2019)

Structure and Drug Resistance of the Plasmodium falciparum Transporter PfCRT
por: Kim, Jonathan, et al.
Publicado: (2019)

Leptin receptor gene polymorphisms c.668A>G and c.1968G>C in Sudanese women with preeclampsia: a case-control study
por: Saad, Amira, et al.
Publicado: (2020)

Factor-V Leiden G1691A and prothrombin G20210A polymorphisms in Sudanese women with preeclampsia, a case -control study
por: Ahmed, Nadir A., et al.
Publicado: (2019)

Analysis of Plasmodium falciparum Pfcrt and Pfmdr1 genes in parasite isolates from asymptomatic individuals in Southeast Nigeria 11 years after withdrawal of chloroquine
por: Ikegbunam, Moses N., et al.
Publicado: (2019)

Use of proscribed chloroquine is associated with an increased risk of pfcrt T76 mutation in some parts of Ghana
por: Asare, Kwame K, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_f9kmmlg3bsn15f1gfmrdocf6h1