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Different methods for administering 17β-estradiol to ovariectomized rats result in opposite effects on ischemic brain damage
BACKGROUND: Numerous stroke studies have controversially shown estrogens to be either neuroprotective or neurodamaging. The discordant results observed in rat brain ischemia models may be a consequence of discrepancies in estrogen administration modes resulting in plasma concentration profiles far f...
Autores principales: | Strom, Jakob O, Theodorsson, Elvar, Holm, Lovisa, Theodorsson, Annette |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848231/ https://www.ncbi.nlm.nih.gov/pubmed/20236508 http://dx.doi.org/10.1186/1471-2202-11-39 |
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