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Analysis of Multiple Sarcoma Expression Datasets: Implications for Classification, Oncogenic Pathway Activation and Chemotherapy Resistance

BACKGROUND: Diagnosis of soft tissue sarcomas (STS) is challenging. Many remain unclassified (not-otherwise-specified, NOS) or grouped in controversial categories such as malignant fibrous histiocytoma (MFH), with unclear therapeutic value. We analyzed several independent microarray datasets, to ide...

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Detalles Bibliográficos
Autores principales: Konstantinopoulos, Panagiotis A., Fountzilas, Elena, Goldsmith, Jeffrey D., Bhasin, Manoj, Pillay, Kamana, Francoeur, Nancy, Libermann, Towia A., Gebhardt, Mark C., Spentzos, Dimitrios
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848563/
https://www.ncbi.nlm.nih.gov/pubmed/20368975
http://dx.doi.org/10.1371/journal.pone.0009747