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Temperature Modulates Plant Defense Responses through NB-LRR Proteins
An elevated growth temperature often inhibits plant defense responses and renders plants more susceptible to pathogens. However, the molecular mechanisms underlying this modulation are unknown. To genetically dissect this regulation, we isolated mutants that retain disease resistance at a higher gro...
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848567/ https://www.ncbi.nlm.nih.gov/pubmed/20368979 http://dx.doi.org/10.1371/journal.ppat.1000844 |
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author | Zhu, Ying Qian, Weiqiang Hua, Jian |
author_facet | Zhu, Ying Qian, Weiqiang Hua, Jian |
author_sort | Zhu, Ying |
collection | PubMed |
description | An elevated growth temperature often inhibits plant defense responses and renders plants more susceptible to pathogens. However, the molecular mechanisms underlying this modulation are unknown. To genetically dissect this regulation, we isolated mutants that retain disease resistance at a higher growth temperature in Arabidopsis. One such heat-stable mutant results from a point mutation in SNC1, a NB-LRR encoding gene similar to disease resistance (R) genes. Similar mutations introduced into a tobacco R gene, N, confer defense responses at elevated temperature. Thus R genes or R-like genes involved in recognition of pathogen effectors are likely the causal temperature-sensitive component in defense responses. This is further supported by snc1 intragenic suppressors that regained temperature sensitivity in defense responses. In addition, the SNC1 and N proteins had a reduction of nuclear accumulation at elevated temperature, which likely contributes to the inhibition of defense responses. These findings identify a plant temperature sensitive component in disease resistance and provide a potential means to generate plants adapting to a broader temperature range. |
format | Text |
id | pubmed-2848567 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-28485672010-04-05 Temperature Modulates Plant Defense Responses through NB-LRR Proteins Zhu, Ying Qian, Weiqiang Hua, Jian PLoS Pathog Research Article An elevated growth temperature often inhibits plant defense responses and renders plants more susceptible to pathogens. However, the molecular mechanisms underlying this modulation are unknown. To genetically dissect this regulation, we isolated mutants that retain disease resistance at a higher growth temperature in Arabidopsis. One such heat-stable mutant results from a point mutation in SNC1, a NB-LRR encoding gene similar to disease resistance (R) genes. Similar mutations introduced into a tobacco R gene, N, confer defense responses at elevated temperature. Thus R genes or R-like genes involved in recognition of pathogen effectors are likely the causal temperature-sensitive component in defense responses. This is further supported by snc1 intragenic suppressors that regained temperature sensitivity in defense responses. In addition, the SNC1 and N proteins had a reduction of nuclear accumulation at elevated temperature, which likely contributes to the inhibition of defense responses. These findings identify a plant temperature sensitive component in disease resistance and provide a potential means to generate plants adapting to a broader temperature range. Public Library of Science 2010-04-01 /pmc/articles/PMC2848567/ /pubmed/20368979 http://dx.doi.org/10.1371/journal.ppat.1000844 Text en Zhu et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Zhu, Ying Qian, Weiqiang Hua, Jian Temperature Modulates Plant Defense Responses through NB-LRR Proteins |
title | Temperature Modulates Plant Defense Responses through NB-LRR Proteins |
title_full | Temperature Modulates Plant Defense Responses through NB-LRR Proteins |
title_fullStr | Temperature Modulates Plant Defense Responses through NB-LRR Proteins |
title_full_unstemmed | Temperature Modulates Plant Defense Responses through NB-LRR Proteins |
title_short | Temperature Modulates Plant Defense Responses through NB-LRR Proteins |
title_sort | temperature modulates plant defense responses through nb-lrr proteins |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848567/ https://www.ncbi.nlm.nih.gov/pubmed/20368979 http://dx.doi.org/10.1371/journal.ppat.1000844 |
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